This type of medication has longer-acting anti-inflammatory effects. It is thought to work by inhibiting the release of inflammatory agents called cytokines by the body’s immune cells in the region where they are injected. Commonly used corticosteroids for joint injections include Kenalog, Aristospan, Celestone, Soluspan, and Depo-Medrol. As long as the patient reduces the activity level of the joints for the first few days after the injection, the medication can last two to three weeks, and can sometimes provide long-term relief.
It is often necessary to repeat joint injections, as the corticosteroids are broken down by the body over time. It has been shown that patients with rheumatoid arthritis who receive corticosteroid injections continue use and function of the affected joints for longer than those who do not. As joint injections are often not a permanent solution, your pain management physician will usually use them in com